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发表于 2024-2-8 12:53:17
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Afipran is metoclopramide?
I’d usually start with something that is antispasmodic the first 1-6 hours of a RGIS episode, fluids and painkillers. Butyscopolamine bromide, (as in buscopan 20 mg/ml injectable) given only once or twice SC, and I give 0,1 ml for rabbits under 3 kg, and 0,2 between 3-4 kg.
This will relax the spasms and allow the gas to move backwards. Famotidine, of course, especially if the rabbit is given NSAIDs. I also tend to use metamizol instead of opiates, to avoid decreasing the natural motility. Warm up the bunny, vibration plate if you have one, peace and quiet. Then, after 3-6 hours I redo the rads and see how the gas and ingesta has moved. Continue tx with analgesia (combo nsaids, metamizol) maybe add maropitant both for analgesia and against nausea.
If I see gas moving back, stomach filled with ingesta and less expansion, temperature go up, these are good signs. Usually at this point the bunnies I treat start nibbling at hay and show less pain signs. I am also very careful to push too much critical care whenever I see these really distended stomachs, just tiny amounts, until things get moving.
Only when I see progress and poop balls starting to form in the distal colon, (usually the buns have already pooped something) I give gastric motility enhances as strong as metoclopramide or cisapride.
The cases that show gas in several compartments (semi obstructions by dry ingesta/hair/etc) are the most difficult, but knock on wood, I’ve had very good results with this treatment the last year and a half.
It takes usually between 1-3 days to work well. If you have the adequate venue with quiet and cozy hospital, good nurses, it is almost infallible for a wide range of RGIS-stages.
I repeat rads and bloods if necessary, to see progress or regress and rethink the therapy. As said, I “save” the motility enhancers until there is free passage, no pain and temperature normalization. If you need the dosages, please say so. Good luck! |
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